Gadgets review: Tools for 3D cell culture

by Alexey Bersenev on November 19, 2013 · 2 comments

in cell culture

Post to Twitter Send Gmail Post to LinkedIn

Since the biggest shift in cell culture from 2D to 3D, there is a boom of tools providers on the market. If you’re doing cell culture and thinking about switching to 3D, you may want to know all currently available tools for it. In this post, I’m going to overview some companies, which make tools and provide services for for 3D cell culture.

MicroTissues
Makes 3D Peptri Dish. Distributed via Sigma-Aldrich. Learn more from videos.

InSphero
Provides 3D organotypic microtissue models and services for liver toxicology testing, oncology and custom applications. Makes and sells kits for 3D culture.

NanoFiber Solutions
Makes and sells 3D labware, based on patented nanofiber scaffolding technology.

Mimetas
Microfluidics‐based 3D culture plates for organ-on-chip research. Provides a technological platform for manual or robotic operations. Learn more from this video.

Nano3D Biosciences Inc
Makes and sells products (labware/ kits) for magnetic levitation 3D culture. 3D cell migration assay. Learn more from this video.

3D Biomatrix
Makes and sells Hanging Drop Plates for multiple 3D applications.

Reinnervate
3D labware, based on porous polysterene scaffold. Also distributed by AMSBIO. Learn more from this video.

3D BioTek
Makes fiber mesh for 3D culture. Labware. Contract lab and manufacturing services.

CellASIC (MIllipore)
Makes and sells microfluidic perfusion plates for 3D culture.

QGelBio
Makes and sells hydrogel – entracellular matrix (ECM) mimetic. Provides assay services.

Bio-Byblos Biomedical
Sells ECM-mimetic for 3D culture.

BD Bioscineces
Makes and sells the most frequently used ECM-mimetic Matrigel.

Also read: Enter the Third Dimension

{ 2 comments… read them below or add one }

Roger November 20, 2013 at 5:11 am

All with their own limitations although the microtissue models are quite interesting. It’s worth mentioning that scaffold-based approaches are most of the times 2,5D and not really 3D.

Reply

Anders November 22, 2013 at 11:29 am

Truly biomimetic 3D models require at least perfusion and layered tissues in coculture. To be useful they should be compatible with readout equipment, automatable and high throughput. None of these seem to deliver in all those areas, except for perhaps mimetas with their organoplates.

Reply

Leave a Comment

Previous post:

Next post: