I continue to review and link to the most highly ranked articles in stem cell research by Faculty Members of online collaborative filter Faculty of 1000.
Today, the Scientist magazine published “Top 7 in Stem Cells” – a snapshot of most highly ranked articles in stem cell research in Faculty of 1000. Most of the highlighted studies done in area of reprogramming – iPS cells and direct transdifferentiation. It indicates the significance and popularity of these directions of stem cell research.
Ok, the current 2010-2011 favorites, mentioned in the Scientist article:
FFa=19
Warren L, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. (Cell Stem Cell 2010 Nov 5; 7(5):618-30)
read more about this paper
read F1000 evaluation
FFa=17
Vierbuchen T, at al. Direct conversion of fibroblasts to functional neurons by defined factors (open access!). (Nature. 2010 Feb 25; 463(7284):1035-41)
learn more about this discovery
FFa=15
Spence JR, et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. (Nature. 2011 Feb 3; 470(7332):105-9)
FFa=14
Szabo E, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. (Nature. 2010 Nov 25; 468(7323):521-6)
read more about this paper
FFa=13
Oshima K, et al. Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells (open access!). (Cell. 2010 May 14; 141(4):704-16)
read F1000 evaluation
FFa=13
Agarwal S, et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients (open access!). (Nature. 2010 Mar 11; 464(7286):292-6)
FFa=13
Melton C, et al. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. (Nature. 2010 Feb 4; 463(7281):621-6)
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Highly ranked 2011 papers, which weren’t mentioned:
FFa=18
Eiraku M, et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. (Nature. 2011 Apr 7; 472(7341):51-6)
FFa=17
Bendall SC, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. (Science. 2011 May 6; 332(6030):687-96)
FFa=15
Warren L, et al. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. (Nature. 2011 May 11)
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Read more about Faculty of 1000 and ranking system.
What do you think about these “hot papers”? What do you think about Faculty of 1000 ranking? Please comment.
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{ 2 comments… read them below or add one }
The paper describing the mRNA only method is an interesting choice as #1 given that I have never talked to or met anyone who can get that approach to work to make human iPS cells. If anyone is out there who uses it successfully, I would really like to hear from you.
Paul
Paul,
I guess the Faculty Members who evaluated this paper didn’t try to reproduce it. Sadly, seem like nobody mentioned Givol’s comment on Cell Stem Cell site and his previous study, which was not cited by Rossi group.