There is an increasing gap between demand of blood and supply of donors worldwide. Today researchers and clinicians are really exciting about the possibility of manufacturing blood cells. Some proof-of-concept research was done and funding organizations quite optimistic about it.
The most promising direction is making red blood cells (RBC) and platelet. There are two main methodological branches for creating RBC artificially – (1) biological or synthetic oxygen carriers and (2) using progenitos or/and stem cells. Recently one more potential method was added – generation of RBC via direct reprogramming of fibroblasts by defined factors.
Please watch this Wellcome Trust video as a teaser:
I’m doing some analysis of this issue and trying to collect independent opinions from professionals. Please express your opinion by taking a poll below. This poll is dedicated to the question of making RBC artificially. But the poll also could be applied for platelet manufacturing (exclude option 1). If you think that different approaches could be applied for RBC and platelet generation, please leave a comment.